CYP2C19

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1.

Conclusion The pharmacodynamic effects of omeprazole and its pharmacokinetics depend on the CYP2C19 genotype status in Chinese volunteers.

结论 CYP2C19 基因多态性对奥美拉唑在中国人体内的药物动力学和药效学有明显影响。

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2.

Plavix does not have its anti-platelet effects until it is metabolized into its active form by the liver enzyme, CYP2C19.

此药必须通过肝酶 CYP2C19 代谢转化为为活性形式才能发挥抗血小板作用。